Life in a post-genomic age has the promise to revolutionize our understanding of how our genes shape who we are, how our genome evolved, and how we function. There are new possibilities for an improved quality of life as we exploit new knowledge to design novel, more effective drugs. Central to thes[...]
Proteins are essential to life, having a great variety of roles in all organisms. They are the ultimate micro-machines: some are building blocks, joining with other substances to make the cells from which we are formed; some are catalysts, speeding up biochemical reactions to keep our cells active a[...]
Our genome is the blueprint to our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. But it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in[...]
A vast amount of biological information about a wide range of species has become available in recent years as technological advances have significantly reduced the time it takes to sequence a genome or determine a novel protein structure. This text describes how bioinformatics can be used as a power[...]